{"created":"2023-05-15T10:25:26.331559+00:00","id":20438,"links":{},"metadata":{"_buckets":{"deposit":"aebab887-ac2b-4667-a665-e047a884297a"},"_deposit":{"created_by":1,"id":"20438","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"20438"},"status":"published"},"_oai":{"id":"oai:u-fukui.repo.nii.ac.jp:00020438","sets":["2392:2393"]},"author_link":["58982","58983","58981","58985","58986","58984"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"1586","bibliographicPageStart":"1581","bibliographicVolumeNumber":"47","bibliographic_titles":[{"bibliographic_title":"Journal of Nuclear Medicine"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"To avoid arterial blood sampling and complicated analyses in 15O-gas PET studies, we evaluated a noninvasive technique using the count-based method for measuring asymmetric increases in oxygen extraction fraction (OEF) in cerebrovascular disease. METHODS: Eighteen patients (mean age +/- SD, 61 +/- 16 y) with atherothrombotic large-cerebral-artery disease were studied for the measurement of hemodynamic parameters using the 15O-gas steady-state method with inhalation of 15O2, C15O2, and C15O. All patients also underwent H2(15)O PET with the bolus injection method. Count-based ratio images of 15O2/C15O2 and (15)O2/H2(15)O were calculated, and asymmetry indices (AIs) were obtained (cbOEF(SS)-AI and cbOEF(BO)-AI, respectively) using regions of interest drawn bilaterally on the cerebral cortices. These AIs were compared with the AIs of absolute OEF (qOEF-AI) and with those after cerebral blood volume (CBV) correction. A contribution factor for this correction was defined as a variable alpha, and the effect of the correction was evaluated. RESULTS: cbOEF(SS)-AI underestimated qOEF-AI significantly, especially with a greater AI (P < 0.05). cbOEF(BO)-AI linearly correlated well with qOEF-AI. CBV correction improved the slopes of regression lines between qOEF-AI and cbOEF(SS)-AI, and the optimal alpha was defined as 0.5. On the other hand, cbOEF(BO)-AI fairly estimated qOEF-AI without CBV correction. Correlation between qOEF-AI and cbOEF(BO)-AI was adversely affected, and the mean bias was increased, with a greater alpha. CONCLUSION: cbOEF(BO)-AI can fairly estimate the AI of OEF without CBV correction, whereas cbOEF(SS)-AI might require CBV correction for better estimation. The examination time and stress to patients would be reduced with the count-based method because it is noninvasive.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Society of Nuclear Medicine"}]},"item_10001_relation_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"TD00006264","subitem_relation_type_select":"NCID"}}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1615505","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_b1a7d7d4d402bcce","subitem_version_type":"AO"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KOBAYASHI, Masato"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OKAZAWA, Hidehiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TSUCHIDA, Tatsuro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KAWAI, Keiichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"FUJIBAYASHI, Yasuhisa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YONEKURA, Yoshiharu"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-08-04"}],"displaytype":"detail","filename":"Okazawa_Diagn.pdf","filesize":[{"value":"257.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Okazawa_Diagn.pdf","url":"https://u-fukui.repo.nii.ac.jp/record/20438/files/Okazawa_Diagn.pdf"},"version_id":"8ab5a180-65fc-4b05-a158-90506f787cd0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"oxygen extraction fraction","subitem_subject_scheme":"Other"},{"subitem_subject":"misery perfusion","subitem_subject_scheme":"Other"},{"subitem_subject":"misery perfusion","subitem_subject_scheme":"Other"},{"subitem_subject":"gas PET study","subitem_subject_scheme":"Other"},{"subitem_subject":"noninvasive method","subitem_subject_scheme":"Other"},{"subitem_subject":"cerebrovascular disease","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"other","resourceuri":"http://purl.org/coar/resource_type/c_1843"}]},"item_title":"Diagnosis of misery perfusion using noninvasive 15O-gas PET.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Diagnosis of misery perfusion using noninvasive 15O-gas PET."}]},"item_type_id":"10001","owner":"1","path":["2393"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-11-30"},"publish_date":"2007-11-30","publish_status":"0","recid":"20438","relation_version_is_last":true,"title":["Diagnosis of misery perfusion using noninvasive 15O-gas PET."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T13:38:53.661490+00:00"}