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Roles of attachment and self-esteem: impact of early life stress on depressive symptoms among Japanese institutionalized children
http://hdl.handle.net/10098/9963
http://hdl.handle.net/10098/99635db6140f-8892-421b-85e7-0ff3b2765191
名前 / ファイル | ライセンス | アクション |
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2505312.pdf (655.5 kB)
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〓 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2016-05-23 | |||||
タイトル | ||||||
タイトル | Roles of attachment and self-esteem: impact of early life stress on depressive symptoms among Japanese institutionalized children | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Child maltreatment | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Reactive attachment disorder | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Voxel-based morphometry | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Grey matter volume | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Visual cortex | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Emotional regulation impairments | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | |||||
資源タイプ | other | |||||
著者 |
Shimada, Koji
× Shimada, Koji× Takiguchi, Shinichiro× Mizushima, Sakae× Fujisawa, Takashi X.× Saito, Daisuke N.× Kosaka, Hirotaka× Okazawa, Hidehiko× Tomoda, Akemi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | hild maltreatment increases the risk for psychiatric disorders throughout childhood and into adulthood. One negative outcome of child maltreatment can be a disorder of emotional functioning, reactive attachment disorder (RAD), where the child displays wary, watchful, and emotionally withdrawn behaviours. Despiteits clinical importance, little is known about the potential neurobiological consequences of RAD. The aim of this study was to elucidate whether RAD was associated with alterations in grey matter volume (GMV). High-resolution magnetic resonance imaging datasets were obtained for children and adolescents with RAD(n = 21; mean age = 12.76 years) and typically developing (TD) control subjects (n = 22; mean age =12.95 years). Using awhole-brain voxel-based morphometry approach, structural images were analysed controlling for age, gender, full scale intelligence quotient, and total brain volume. The GMVwas significantly reduced by 20.6% in the left primary visual cortex (Brodmann area 17) of the RAD group compared to the TD group (p=.038, family-wise error-corrected cluster level). This GMV reduction was related to an internalising problem measure of the Strength and Difficulties Questionnaire. The visual cortex has been viewed as part of the neurocircuit regulating the stress response to emotional visual images. Combinedwith previous studies of adultswith childhood maltreatment, early adverse experience (e.g. sensory deprivation) may affect the development of the primary visual system, reflecting in the size of the visual cortex in children and adolescents with RAD. These visual cortex GMV abnormalities may also be associated with the visual emotion regulation impairments of RAD, leading to an increased risk for later psychopathology. | |||||
書誌情報 |
NeuroImage: Clinical 巻 9, p. 13-19, 発行日 2015-07 |
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出版者 | ||||||
出版者 | Elsevier Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 22131582 | |||||
書誌レコードID | ||||||
識別子タイプ | NCID | |||||
関連識別子 | TD00000766 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.nicl.2015.07.001 | |||||
著者版フラグ | ||||||
出版タイプ | AO | |||||
出版タイプResource | http://purl.org/coar/version/c_b1a7d7d4d402bcce |