In radiation therapy for cervical cancer, acute radiation-induced enterocolitis may cause treatment interruption. To evaluate the relevance between body fat and acute radiation-induced enterocolitis in cervical cancer patients, patient backgrounds, surgical results, total irradiation dose, and fat area were extracted from 18 patients who underwent radical hysterectomy followed by radiotherapy (postoperative RT group), 38 patients who underwent radical hysterectomy followed by concurrent hemoradiotherapy (CCRT) (postoperative CCRT group), and 34 patients who received only radical concurrent chemoradiotherapy (CCRT alone group), and were compared retrospectively for the presence of Grade 2 or higher diarrhea. In the postoperative CCRT group, diarrhea of Grade 2 or higher was observed in 57.9% (22/38) of patients. The group with Grade 2 or higher diarrhea had significantly less total and visceral fat area than the group without diarrhea. In the postoperative RT and the CCRT alone groups, there was no significant difference between the presence of Grade2 or higher diarrhea and total/visceral fat area. CCRT after radical hysterectomy in patients with low body and visceral fat content was suggested to cause Grade 2 or higher diarrhea.
雑誌名
福井大学医学部研究雑誌
雑誌名(英)
Journal of Interdisciplinary Research of the School of Medical Sciences, University of Fukui
体脂肪と子宮頸癌の急性期放射線性腸炎との検討
BD10126519.pdf
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