This study investigates how hospital employees' psychological factors and organizational climate can influence employees with regard to the adoption of new medical devices. We consider two contextual dimensions of employees' self-sacrifice and crossfunctional cooperation as intrinsic components for hospital organizations. The hypotheses were tested with hierarchical regression analysis based on survey data from 207 employees at Japanese hospitals. The findings demonstrate that the relationship between cross-functional cooperation and the intention of new medical device adoption is suppressed in case of higher levels of self-sacrifice. The interpretation of this result is that hospital employees who show high levels of self-sacrifice tend to restrain their acceptance of new medical devices in order to give more consideration to the involvement of other departments. Based on these findings, this research suggests that it is critical for hospitals and medical device suppliers which intend to prompt the introduction of new medical devices to consider both the aspect of employees' self-sacrifice as well as the cross-functional cooperation in hospital organizations.